Necrotizing Enterocolitis: Insights Into Pathogenesis, Diagnosis and Treatment

Necrotizing Enterocolitis: Insights Into Pathogenesis, Diagnosis and Treatment

Author: David J Hackam

Format: Hardcover

Pages: 300

ISBN: 9789814725941

Publisher: World Scientific Publishing Company

Release Date: December 31, 2017

Description du Livre

Necrotizing enterocolitis (NEC), described over 30 years ago, remains the leading cause of death in premature infants from gastrointestinal disease. It is axiomatic that NEC is both a devastatingly serious disease and one in which its very underpinnings remain a mystery.The disease develops quickly and without warning. Every clinician who takes care of neonates will attest to the typical scenario of a premature infant who is at first clinically stable, then subtly begins to manifest a series of symptoms which progress — often quite rapidly — from feeding intolerance, abdominal distention and bloody stools, to outright sepsis and hemodynamic instability. Every surgeon who operates on these fragile patients will have experienced the scenario where laparotomy reveals the presence of patchy necrosis of the intestine with a distribution and severity which may or may not match the clinical impression that was present preoperatively. A large number of studies have revealed that neither the type of surgery that is performed on patients with NEC, nor its timing, can significantly alter outcomes in patients with this disease. These clinical impressions reveal the highly variable nature of patients with NEC, and also underscore the fact that if we are to improve the outcome of these young children, then a clearer understanding of the pathogenesis of NEC at the molecular level is required.This textbook will focus on all major schools of thought regarding the factors that lead to the development of NEC, and will address the current scientific approach to the development of appropriate treatments. In addition, this book will address the complex social, ethical, nursing and rehabilitative issues that clinicians face when caring for patients with NEC. Finally, a significant focus of the book will be devoted to the scientific underpinnings of this disease, and the successes so far in the development of novel therapeutic approaches based upon these scientific discoveries.

Commentaires
Émilie Aucoin
Mes amis sont tellement fous qu’ils ne savent pas comment j’ai tous les ebook de haute qualité qu’ils n’ont pas!
Alphonse Ratté
Je tiens à vous remercier personnellement pour vos livres exceptionnels. C’est vraiment merveilleux.
Blanchefle Morneau
Enfin, je reçois cet ebook, merci pour tous ces miracles de Noël que je peux obtenir maintenant!
Gradasso Martel
Leur Miracle de Noel était le meilleur livre que j’ai jamais acheter. Leur Miracle de Noel a fait exactement ce que tu as dit qu’il faisait.
Andrée Bédard
Je vous recommanderai à mes collègues. Leur miracle de Noël est les livres les plus précieux que nous ayons jamais achetés. Je serais perdu sans ça. Je suis complète ment époustouflé.